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国家神经疾病医学中心National Center for Neurological Disorders

中国国际神经科学研究所China International Neuroscience Institute

国家老年疾病临床医学研究中心National Clinical Research Center for Geriatric Diseases

贾建平

科室: 神经内科 查看科室详情

职称:主任医师

专长:阿茨海默病及认知障碍疾病、脑血管病、神经科疑难病

常规出诊时间:

联系电话:83198277 科室位置:北京市西城区长椿街45号宣武医院
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个人简历

  主任医师,教授,神经疾病高创中心科主任

  专业特长:

  贾建平是一位临床经验丰富和科学理论精到的临床科学家,中央保健医生,2018年被评为国之名医,从事神经科临床工作30余年,长期的临床实践造就了精湛的医疗技术,一直在临床第一线工作,经治了来自全国各地疑难病患者,参加数以万计的国内外会诊,对常见病、多发病、疑难杂症的诊治有独到的临床思维和绝技,倡导“每个疾病千差万别,要带着研究的态度来看病”,这一观点曾被中央电视台《东方之子》栏目组作过全面报道,被同行和社会民众公认为神经科代表性人物。

  科研与教学水平:

  先后主持并参与了国家自然科学基金委员会重点重大项目五项,973等科技部项目十余项,其他省部级项目十余项,发表相关论文960余篇,其中SCI 257篇,在Lancet Neurology,Lancet Public Health,Alzheimer & Dementia,Nature Communications,Brain等著名学术期刊发表IF≥10分27篇,总被引16000余次。连续主编全国高等医学院校《神经病学》教材第6、7、8版及其他教材、著作共56部,被称为我国神经病学教材主编第一人。

  个人荣誉:

  担任中华医学会神经病学分会主任委员(2007年候任主委,2010年任主委,2013年任前任主委,2016年任名誉主委)、中国医师协会神经内科分会会长(2004年会长,2009年连任会长,2017年-至今任前任会长)、北京医学会神经病学分会主任委员、中华医学会神经病学分会痴呆与认知障碍学组组长、中国医师协会神经内科医师分会认知障碍疾病专业委员会主任委员。担任首都医科大学神经病学系主任、首都医科大学神经变性病与记忆障碍疾病临床诊疗与研究中心主任、首都医科大学神经病学研究所所长、北京脑重大疾病研究院阿尔茨海默病研究所所长、老年认知障碍疾病北京重点实验室主任。以及《Alzheimer’s & Dementia》、《Alzheimer’s Research & Therapy》、《Current Alzheimer Research》、《Journal of Alzheimer’s Disease》、《中华神经科杂志》、《中华医学杂志》等20种学术刊物的主编、副主编及编委等多项学术团体职务。先后获得国家科学技术进步奖二等奖、国之名医、药明康德生命化学研究奖、中国杰出神经内科医师学术成就奖、北京市十百千人才十层次人才、北京市卫生系统高层次领军人才、国务院政府特殊津贴专家、中国医师奖等二十余项荣誉。

  代表性论著:

  1. Jia L, Zhu M, Kong C, Pang Y, Zhang H, Qiu Q, Wei C, Tang Y, Wang Q, Li Y, Li T, Li F, Wang Q, Li Y, Wei Y, Jia J*. Blood neuro-exosomal synaptic proteins predict Alzheimer’s disease at the asymptomatic stage. Alzheimers Dement. Dement.2021; 17(1):49-60

  2. Jia L, Quan M, Fu Y, Zhao T, Li Y, Wei C, Tang Y, Qin Q, Wang F, Qiao Y, Shi S, Wang YJ, Du Y, Zhang J, Zhang J, Luo B, Qu Q, Zhou C, Gauthier S, Jia J*, Group for the Project of Dementia Situation in C. Dementia in China: epidemiology, clinical management, and research advances. Lancet Neurol. 2020; 19:81-92.

  3. Jia L, Fu Y, Shen L, Zhang H, Zhu M, Qiu Q, Wang Q, Yan X, Kong C, Hao J, Wei C, Tang Y, Qin W, Li Y, Wang F, Guo D, Zhou A, Zuo X, Yu Y, Li D, Zhao L, Jin H, Jia J*. PSEN1, PSEN2, and APP mutations in 404 Chinese pedigrees with familial Alzheimer's disease. Alzheimers Dement. 2020;16(1):178-91.

  4. Jia L, Xu H, Chen S, Wang X, Yang J, Gong M, Wei C, Tang Y, Qu Q, Chu L, Shen L, Zhou C, Wang Q, Zhao T, Zhou A, Li Y, Li F, Li Y, Jin H, Qin Q, Jiao H, Li Y, Zhang H, Lyu D, Shi Y, Song Y, Jia J*. The APOE-ε4 exerts differential effects on familial and other subtypes of Alzheimer’s disease. Alzheimers Dement. 2020. DOI: 10.1002/alz.12153.

  5. Jia L, Du Y, Chu L, Zhang Z, Li F, Lyu D, Li Y, Li Y, Zhu M, Jiao H, Song Y, Shi Y, Zhang H, Gong M, Wei C, Tang Y, Fang B, Guo D, Wang F, Zhou A, Chu C, Zuo X, Yu Y, Yuan Q, Wang W, Li F, Shi S, Yang H, Zhou C, Liao Z, Lv Y, Li Y, Kan M, Zhao H, Wang S, Yang S, Li H, Liu Z, Wang Q, Qin W, Jia J; COAST Group. Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study. Lancet Public Health. 2020;5(12):e661-e671.

  6. Jia L, Li F, Wei C, Zhu M, Qu Q, Qin W, Tang Y, Shen L, Wang Y, Shen L, Li H, Peng D, Tan L, Luo B, Guo Q, Tang M, Du Y, Zhang J, Zhang J, Lyu J, Li Y, Zhou A, Wang F, Chu C, Song H, Wu L, Zuo X, Han Y, Liang J, Wang Q, Jin H, Wang W, Lü Y, Li F, Zhou Y, Zhang W, Liao Z, Qiu Q, Li Y, Kong C, Li Y, Jiao H, Lu J, Jia J*. Prediction of Alzheimer's disease using multi-variants from a Chinese genome-wide association study. Brain. 2020. DOI: 10.1093/brain/awaa364

  7. Jia L, Qiu Q, Zhang H, Chu L, Du Y, Zhang J, Zhou C, Liang F, Shi S, Wang S, Qin W, Wang Q, Li F, Wang Q, Li Y, Shen L, Wei Y, Jia J*. Concordance between the assessment of Abeta42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid. Alzheimers Dement. 2019;15(8):1071-80.

  8. Tang Y, Xing Y, Zhu Z, He Y, Li F, Yang J, Liu Q, Li F, Teipel S, Zhao G, Jia J*. The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial. Alzheimers Dement. 2019;15(5):605-14.

  9. Wang Z, Gong K, Liu X, Zhang Z, Sun X, Wei Z, Yu S, Manfredsson FP, Sandoval IM, Johnson PF, Jia J*, Wang J, Ye K. C/EBPbeta regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease. Nat Commun. 2018;9(1):1784.

  10. Jia J*, Wei C, Chen S, Li F, Tang Y, Qin W, Zhao L, Jin H, Xu H, Wang F, Zhou A, Zuo X, Wu L, Han Y, Han Y, Huang L, Wang Q, Li D, Chu C, Shi L, Gong M, Du Y, Zhang J, Zhang J, Zhou C, Lv J, Lv Y, Xie H, Ji Y, Li F, Yu E, Luo B, Wang Y, Yang S, Qu Q, Guo Q, Liang F, Zhang J, Tan L, Shen L, Zhang K, Zhang J, Peng D, Tang M, Lv P, Fang B, Chu L, Jia L, Gauthier S. The cost of Alzheimer's disease in China and re-estimation of costs worldwide. Alzheimers Dement. 2018;14(4):483-91.

  11. Jia J*, Gauthier S, Pallotta S, Ji Y, Wei W, Xiao S, Peng D, Guo Q, Wu L, Chen S, Kuang W, Zhang J, Wei C, Tang Y. Consensus-based recommendations for the management of rapid cognitive decline due to Alzheimer's disease. Alzheimers Dement. 2017:592-7.

  12. Jia J*, Zuo X, Jia XF, Chu C, Wu L, Zhou A, Wei C, Tang Y, Li D, Qin W, Song H, Ma Q, Li J, Sun Y, Min B, Xue S, Xu E, Yuan Q, Wang M, Huang X, Fan C, Liu J, Ren Y, Jia Q, Wang Q, Jiao L, Xing Y, Wu X, China C, Aging Study G. Diagnosis and treatment of dementia in neurology outpatient departments of general hospitals in China. Alzheimers Dement. 2016;12(4):446-53.

  13. Jia J*, Wei C, Liang J, Zhou A, Zuo X, Song H, Wu L, Chen X, Chen S, Zhang J, Wu J, Wang K, Chu L, Peng D, Lv P, Guo H, Niu X, Chen Y, Dong W, Han X, Fang B, Peng M, Li D, Jia Q, Huang L. The effects of DL-3-n-butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease: A multicentre, randomized, double-blind, placebo-controlled trial. Alzheimers Dement. 2016;12(2):89-99.

  14. Zhang Z, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun YE, Ping Yu S, Jia J*, Levey AI, Ye K. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762.

  15. Tang Y, Wang X, Jia J*. Mercury poisoning presenting as sporadic Creutzfeldt-Jakob disease: a case report. Ann Intern Med. 2015;162(6):462-3.

  16. Jia J*, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014;10(4):439-47.

  17. Jia J*, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement. 2014;10(1):1-9.

  18. Xing Y, Jia J*, Ji, X, Tian, T. Estrogen associated gene polymorphisms and their interactions in the progress of Alzheimer's disease. Prog Neurobiol. 2013;111:53-74.

  19. Jia J, Pollock M, Jia JM. Cold injury to nerves is not due to ischaemia alone. Brain. 1998;121: 989-1001.

  20. Jia J, Pollock M. The pathogenesis of non-freezing cold nerve injury. Observations in the rat. Brain. 1997;120: 631-46.

  21. 中华医学会神经病学分会痴呆与认知障碍学组写作组,贾建平*. 血管性认知障碍诊治指南. 中华神经科杂志. 2011, 44(2): 141-147.

  22. 贾建平主编. 中国痴呆与认知障碍诊治指南:人民卫生出版社,2010,北京.

  23. 贾建平主编. 中国痴呆与认知障碍诊治指南(2015年版):人民卫生出版社,2016,北京.

  24. 贾建平,陈生弟主编. 神经病学(第8版):人民卫生出版社,2018,北京.

  25. 贾建平,陈生弟主编. 神经病学(第7版):人民卫生出版社,2013,北京.

  26. 贾建平主编. 神经病学(第6版):人民卫生出版社,2008,北京.


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